Publications
:: Publications



The following publications represent the findings we have learned from the CaMos data so far.


1.Cadarette SM, Jaglal SB and Murray TM (1999) Validation of the simple calculated osteoporosis risk estimation (SCORE) for patient selection of bone densitometry. Osteoporos Int 10(1):85-90.

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2.Kreiger N, Tenenhouse A, Joseph L, Mackenzie T, Poliquin S, Brown JP, Prior JC, Rittmaster RS (1999) The Canadian Multicentre Osteoporosis Study (CaMos): Background, Rationale, Methods. Can J Aging 18(3):376-387.

3.Tenenhouse A, Kreiger N, Hanley D. Canadian Multicentre Osteoporosis Study (CaMos) (2000) Drug Development Research 49(3):201-205.

4.Hopman W, Towheed T, Anastassiades T, Tenenhouse A, Poliquin S, Berger C, Joseph L, Brown J, Murray T, Adachi JD, Hanley D, Papadimitropoulos M, CaMos Research Group (2000) Canadian Normative Data for the SF-36 Health Survey. CMAJ 163(3):265-71.

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5.Cadarette SM, Jaglal SB, Kreiger N, McIsaac WJ, Darlington GA, Tu JV (2000) Development and Validation of the Osteoporosis Risk Assessment Instrument to Facilitate Selection of Women for Bone Densitometry, CMAJ 162 (9):1289-94.

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6.Jackson SA, Tenenhouse A, Robertson L and the CaMos Study Group (2000) Vertebral Fracture Definition from Population-Based Data: Preliminary Results from the Canadian Multicenter Osteoporosis Study (CaMos). Osteoporos Int 11(8):680-687.

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7.Tenenhouse A, Joseph L, Kreiger N, Poliquin S, Murray TM, Blondeau L, Berger C, Hanley DA, Prior JC and the CaMos Research Group (2000) Estimation of the Prevalence of Low Bone Density in Canadian Women and Men Using a Population-Specific DXA Reference Standard: The Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int 11(10):897-904.

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8.Cadarette S M, Jaglal SB, Murray T M, McIsaac WJ, Joseph L, Brown JP, for the Canadian Multicentre Osteoporosis Study (CaMos) (2001) Evaluation of Decision Rules for Referring Women for Bone Densitometry by Dual-Energy X-ray Absorptiometry. JAMA 286(1):57-63.

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9.Prior JC, Kirkland SA, Joseph L, Kreiger K, Murray TM, Hanley DA, Adachi JD, Vigna YM, Berger C, Blondeau L, Jackson SA, Tenenhouse A (2001) for the CaMos Research Group. Oral Contraceptive Use and Bone Mineral Density in Premenopausal Women: Cross-sectional, population-based data from the Candaian Multicentre Osteoporosis Study. CMAJ 165(8):1023-1029.

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10.Adachi JD, Ioannidis G, Berger C, Joseph L, Papaioannou A, Pickard L, Papadimitropoulos E, Hopman W, Poliquin S, Prior JC, Hanley DA, Olszynski WP, Anastassiades T, Brown JP, Murray T, Tenenhouse A, and the Canadian Multicentre Osteoporosis Study (CaMos) Research Group (2001) The Influence of Osteoporotic Fractures on Health-Related Quality of Life in Community Dwelling Men and Women Across Canada. Osteoporos Int 12 (11):903-908

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11.Hopman W, Berger C, Joseph L, Towheed T, Anastassiades T, Tenenhouse A, Poliquin S, Brown J, Murray T, Adachi JD, Hanley D, Papadimitropoulos M, CaMos Research Group (2002) Is There Regional Variation in the SF-36 Scores of Canadian Adults? CJPH 93(3): 233-237.

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12.Kmetic A, Joseph L, Berger C, Tenenhouse A (2002) Multiple Imputation to Account for Missing Data in a Survey: Estimating the Prevalence of Osteoporosis. Epidemiology 13(4):437-444

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13.Rucker D, Allan J A, Fick G H, Hanley D A (2002) Vitamin D insufficiency in a population of Healthy Western Canadians. CMAJ 166(12): 1517-1524.

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14.Kanis JA, Black D, Cooper C, Dargent P, Dawson-Hughes B, De Laet C, Delmas P, Eisman J, Johnell O, Jonsson B, Melton J, Oden A, Papapoulos S, Pols H, Rizzoli R, Silman A, Tenenhouse A, on behalf of the International Osteoporosis Foundation and the National Osteoporosis Foundation, USA (2002) A New Approach to the Development of Assessment Guidelines for Osteoporosis. Osteoporos Int 13(7): 527-536.

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15.Hanley DA, Brown, JP, Tenenhouse A, Olszynski WP, Ioannidis G, Berger C, Prior JC, Pickard L, Murray TM, Anastassiades T, Kirkland S, Joyce C, Joseph L, Papaioannou A, Jackson SA, Poliquin S, Adachi JD and The Canadian Multicentre Osteoporosis Study (CaMos) Research Group (2003) Associations Among Disease Conditions, Bone Mineral Density, and Prevalent Vertebral Deformities in Men and Women 50 years of Age and Older: Cross-Sectional Results From the Canadian Multicentre Osteoporosis Study. J Bone Miner Res 18 (4):784-790.

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16.Adachi JD, Ioannidis G, Pickard L, Berger C, Prior JC, Joseph L Hanley DA, Olszynski WP, Murray TM, Anastassiades T, Brown JP, Kirkland S, Joyce C, Papaioannou A, Poliquin S, Tenenhouse A, Papadimitropoulos EA and the Canadian Multicentre Osteopororsis Study (CaMos) Research Group (2003) The Association Between Osteoporotic Fractures and Health-related Quality of Life as Measured by the Health Utilities Index in the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int 14(11):894-904.

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17.VanDenKerkhof EG, Hopman WM, Towheed TE, Anastassiades TP, Goldstein DH and the Canadian Multicentre Osteoporosis Study Research Group (2003) The impact of sampling and measurement on the prevalence of self-reported pain in Canada. Pain Res Manage 8(3):157-163.

18.Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Melton III L J, Tenenhouse A, Reeve J, Silman A, Pols HAP, Eisman JA, McCloskey EV, Mellstrom D (2004) A Meta-analysis of prior corticosteroid use and fracture risk. JBMR 19(6):893-9. Epub 2004 Jan 27.

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19.Rucker D, Ezzat S, Diamandi A, Khosravi J, Hanley DA (2004) IGF-I and testosterone levels as predictors of bone mineral density in healthy, community-dwelling men. Clin Endocrinol (Oxf) 60(4):491-9.

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20.Nadalin V, Bentvelson K, Kreiger N, Reliability of self-reports: Data from the Canadian Multi-Centre Osteoporosis Satudy (CaMos) (2004) Chronic Diseases in Canada 25(2):28-31.

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21.Kanis JA, Johnell O, Oden A, Johansson H, De Laet C, Eisman JA, Fujiwara S, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2005) Smoking and fracture risk: a meta-analysis. Osteoporos Int 16(2):155-62. Epub 2004 June 3.

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22.Kanis JA, Johnell O, de Laet C, Johansson H, Oden A, Delmas P, Eisman J, Fujiwara S, Garnero P, Kroger H, McCloskey EV, Mellstrom D, Melton LJ, Pols H, Reeve J, Silman A, Tenenhouse A (2004) A Meta-analysis of Previous Fracture and Subsequent Fracture Risk. Bone 35(2):375-82.

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23.Hopman W M , Berger C , Joseph L, Towheed T, vandenKerkhof E, Anastassiades T , Cranney A, Adachi J D, Ioannidis G, Poliquin S , Brown JP, Murray TM , Hanley DA, Papadimitropoulos EA, Tenenhouse A, and the CaMos Research Group (2004) Stability of Normative Data for the SF-36: Results of a Three-Year Prospective Study in Middle-Aged Canadians. CJPH 95(5):387-391.

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24.Kanis JA, Johansson H, Johnell O, Oden A, De Laet C, Eisman JA, Pols H, Tenenhouse A (2005) Alcohol intake as a risk factor for fracture.Osteoporos Int 16(7):799-804. Epub 2004 Sep 29.

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25.Kanis JA, Johansson H, Oden A, De Laet C, Johnell O, Eisman JA, McCloskey E, Mellstrom D, Pols H, Reeve J, Silman A, Tenenhouse A (2005) A meta-analysis of milk intake and fracture risk: low utility for case finding. Osteoporos Int 16(7):799-804. Epub 2004 Oct 21.

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26.Papaioannou A, Joseph L, et al Ioannidis G, Berger C, Anastassiades T, Brown JP, Hanley DA, Hopman W, Josse RG, Kirkland S, Murray TM, Olszynski WP, Pickard L, Prior JC, Siminoski K, Adachi JD (2005) Risk factors associated with incident clinical vertebral and nonvertebral fractures in postmenopausal women: the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int 16:568-578. Epub 2004 October 27.

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27.Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Eisman JA, McCloskey EV, Mellstrom D, Melton LJ 3rd, Pols HA, Reeve J, Silman AJ, Tenenhouse A (2004) A family history of fracture and fracture risk: a meta-analysis.Bone Nov;35(5):1029-37.

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28.Ettinger B, Hillier TA, Pressman A, Che M, Hanley DA (2005) Simple computer model for calculating and reporting 5-year osteoporotic fracture risk in postmenopausal women. J Womens Health (Larchmt) 14(2):159-71.

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29.Johnell O, Kanis JA, Oden A, Johansson H, De Laet C, Delmas P, Eisman JA, Fujiwara S, Kroger H, Mellstrom D, Meunier PJ, Melton LJ 3rd, O’Neill T, Pols H, Reeve J, Silman A, Tenenhouse A (2005) Predictive value of BMD for hip and other fractures. J Bone Miner Res Jul;20(7):1185-94. Epub 2005 Mar 7.

30.De Laet C, Kanis JA, Oden A, Johanson H, Johnell O, Delmas P, Eisman JA, Kroger H, Fujiwara S, Garnero P, McCloskey EV, Mellstrom D, Melton LJ 3rd, Meunier PJ, Pols HA, Reeve J, Silman A, Tenenhouse A (2005) Body mass index as a predictor of fracture risk: A meta-analysis. Osteoporos Int Nov;16(11):1330-8. Epub 2005 Jun 1.

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31.Groll D, To T, Bombardier C, Wright J (2005) The development of a comorbidity index with physical function as the outcome. J Clin Epi 58(6): 595-602.

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32.Sawka AM, Thabane L, Papaioannou A, Gafni A, Ioannidis G, Papadimitropoulos EA, Hopman WM, Cranney A, Hanley DA, Pickard L, Adachi JD (2005) Health-related quality of life measurements in elderly Canadians with osteoporosis compared to other chronic medical conditions: a population-based study from the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int Dec; 16(12):1836-40. Epub 2005 Aug18.

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33.Kanis JA, Johnell O, Oden A, Johansson H, Eisman JA, Fujiwara S, Kroger H, Honkanen R, Silman A, Tenenhouse A (2006) The use of multiple sites for the diagnosis of ostoporosis. Osteoporos Int 17(4):527-34. Epub 2006 Jan 10.

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34.Hopman WM, Berger C, Joseph L, Towheed T, Vandenkerkhof E, Anastassiades T, Adachi JD, Ioannidis G, Brown JP, Hanley DA, Papadimitrpoulos EA, the CaMos Research Group (2006) The Natural Progression of Health Related Quality of Life: Results of a Five-Year Prospective Study of SF36 Scores in a Normative Population. Qual Life Res 15:527-536.

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35.Richards JB, Joseph L, Schwartzman K, Kreiger N, Tenenhouse A, Goltzman D; For the Canadian Multicentre Osteoporosis Study (CaMos) (2006) The effect of cyclooxygenase-2 inhibitors on bone mineral density: results from the Canadian Multicentre Osteoporosis Study. Osteoporos Int Sep;17(9):1410-9. Epub 2006 Jun 22.

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36.Sawka AM, Papaioannou A, Josse RG, Murray TM, Ioannidis G, Hanley DA, Prior JC, Thabane L, Papadimitropoulos EA, Gafni A, Pickard L, Anastassiades T, Kirkland S, Adachi JD, The CaMos Research Group (2006) What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos. J Clin Densitom Oct-Dec;9(4):413-8. Epub 2006 Sep 1.

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37.Hopman WM, Towheed TE, Gao Y, Berger C, Joseph L, Vik SA, Hanley DA, Carran J, Anastassiades T (2006) Prevalence of and factors associated with glucosamine use in Canada. Osteoarthritis and Cartilage Dec; 14(12):1288-93. Epub 2006 July 8

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38.Richards JB, Papaioannou A, Adachi J, Joseph L, Whitson H, Prior J, Goltzman D, CaMos Research Group (2007) Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med Jan 22; 167(2):188-94.

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39.Richards JB, Leslie WD, Joseph L, Siminoski K, Hanley DA, Adachi JD, Brown JP, Morin S, Papaioannou A, Josse RG, Prior JC, Davison KS, Tenenhouse A, Goltzman D, CaMos Study Group (2007) Changes to osteoporosis prevalence according to method of risk assessment. J Bone Miner Res Feb;22(2):228-34.

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40.Kanis JA, Oden A, Johnell O, Johansson H, De Laet C, Brown J, Burckhardt P, Cooper C, Christiansen C, Cummings S, Eisman JA, Fujiwara S, Gluer C, Goltzman D, Hans D, Krieg MA, La Croix A, McCloskey E, Mellstrom D, Melton LJ 3rd, Pols H, Reeve J, Sanders K, Schott AM, Silman A, Torgerson D, van Staa T, Watts NB, Yoshimura N (2007) The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporos Int Aug;18(8):1033-46. [Epub 2007 Feb 24].

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41.Hopman WM, Leroux C, Berger C, Joseph L, Barr SI, Prior JC,, Harrison M, Poliquin S, Towheed T, Anastassiades T, Goltzman D, CaMos Research Group (2007) Changes in Body Mass Index in Canadians Over a Five-Year Period: Results of a prospective, Population-Based Study.BMC Public Health 7:150.

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42.Prior JC, Burdge DR, Maan E, Milner R, Hankins C, Klein M, Walmsley S, Canadian Women’s HIV Study Group, CaMos Research Group (2007) Fragility fractures and bone mineral density in HIV positive women: A case control population-based study. Osteoporos Int Oct; 1345(10):1345-53.

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43.Hopman WM, Berger C, Joseph L, Barr SI, Gao Y, Prior JC, Poliquin S, Towheed T, Anastassiades T (2007) The association between body mass index and health-related quality of life: data from CaMos, a stratified population study. Qual Life Res Dec; 16(10):1595-603.

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44.Papaioannou A, Kennedy CC, Ioannidis G, Gao Y, Sawka AM, Goltzman D, Tenenhouse A, Pickard L, Olszynski WP, Davison KS, Kaiser S, Josse RG, Kreiger N, Hanley DA, Prior JC, Brown JP, Anastassiades T, Adachi JD, CaMos Research Group (2008) The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study. Osteoporos Int 19 (4):581-7

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45.Berger C, Langsetmo L, Joseph L, Hanley DA, Davison SK, Josse R, Kreiger N, Tenenhouse A, Goltzman D and the Canadian Multicentre Osteoporosis Study Research Group (2008) Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents. CMAJ 178(13):1660-1668.

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46.Langsetmo L, Hanley DA, Kreiger N, Jamal SA, Prior J, Adachi JD, Davison KS, Kovacs C, Anastassiades T, Tenenhouse A, Goltzman D; CaMos Research Group. (2008) Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older. Bone Oct;43(4):672-8.

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47.Whitson HE, Sanders L, Pieper CF, Gold DT, Papaioannou A, Richards JB, Adachi JD, Lyles KW; CaMos Research Group.(2008) Depressive symptomatology and fracture risk in community-dwelling older men and women. Aging Clin Exp Res. Dec;20(6):585-92.

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48.Langsetmo LA, Morin S, Richards JB, Davison KS, Olszynski WP, Prior JC, Josse R, Goltzman D, CaMos Research Group. (2009) Effectiveness of antiresorptives for the prevention of nonvertebral low-trauma fractures in a population-based cohort of women.Osteoporos Int Feb;20(2):283-90. [Epub 2007 Jun 26]

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49.Berger C, Langsetmo L, Joseph L, Hanley DA, Davison SK, Josse RJ, Prior JC, Kreiger N, Tenenhouse A, Goltzman D and the CaMos Research Group (2009) Association Between Change in BMD and Fragility Fracture in Women and Men. J Bone Miner Res Feb;24:361-370. [Epub 2008 Oct 10]

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50.Chen P, Krege JH, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Papadimitropoulos E, Kreiger N, Olszynski WP, Josse RG, Goltzman D; CaMOS Research Group. (2009) Vertebral fracture status and the world health organization risk factors for predicting osteoporotic fracture risk. J Bone Miner Res. Mar;24(3):495-502.

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51.Poliquin S, Joseph L, Gray-Donald K. (2009) Calcium and vitamin D intakes in an adult Canadian population. Can J Diet Pract Res. Spring;70(1):21-7.

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52.Papaioannou A, Kennedy CC, Ioannidis G, Sawka A, Hopman WM, Pickard L, Brown JP, Josse RG, Kaiser S, Anastassiades T, Goltzman D, Papadimitropoulos M, Tenenhouse A, Prior JC, Olszynski WP, Adachi JD; CaMos Study Group.The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study.Osteoporos Int. 2009 May;20(5):703-14. [Epub 2008 Sep 19]

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53.Jamal SA, Goltzman D, Hanley DA, Papaioannou A, Prior JC, Josse RG. (2009)Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study.Osteoporos Int. May;20(5):737-44.[Epub 2008 Sep 18]

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54.Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD. (2009) Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ, Sep; 181(5):265-71.

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55.Langsetmo L, Goltzman D, Kovacs CS, Adachi JD, Hanley DA, Kreiger N , Josse R, Papaioannou A, Olszynski WP, Jamal SA and the CaMos Research Group. Repeat low-trauma fractures occur frequently among men and women who have osteopenic bone mineral density. JBMR Sep;24(9):1515-22 [Epub 2009 March 30]

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56.Kingwell E, Prior JC, Ratner PA, Kennedy SM. (2010) Direct-to-participant feedback and awareness of bone mineral density testing results in a population-based sample of mid-aged Canadians. Osteoporos Int. OI Feb; 21(2):307-19 (Epub 2009 Jun 4)

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57.Jamal SA, Swan VJ, Brown JP, Hanley DA, Prior JC, Papaioannou A, Langsetmo L, Josse RG; Canadian Multicentre Osteoporosis Study Research Group. (2010) Kidney function and rate of bone loss at the hip and spine: the Canadian Multicentre Osteoporosis Study. Am J Kidney Dis. 2010 Feb;55(2): 291-9 (Epub 2009 Dec 30)

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:: Osteoporosis


Osteoporosis is a condition of excessive skeletal fragility resulting in bones that break easily.

A combination of genetic, dietary, hormonal, age-related, and lifestyle factors all contribute to this condition. The osteoporosis seen in postmenopausal women is the most common and best-studied, but there are other causes that may be treated differently.