The Toronto Centre is located at:

Dr. Robert G. Josse Centre Director

Dr. Sophie Jamal Centre Co-Director

Ms. Barbara Gardner-Bray Centre Coordinator

:: Participants

Men and women, aged 25 years and older, recruited from 1995 to 1997, residing within a 50 km radius of one of nine designated clinical centres, contacted at random by phone.

Youth cohort: men and women, aged 16-24 recruited from 2004-2006.

:: Data Collection

At baseline, year 3 (for participants 40-60), year 5 and year 10, a long questionnaire was administered to all consenting participants.

Bone density was measured using DXA (dual-energy X-ray absorptiometry) at the lumbar spine and hip, and ultrasound of the shin and wrist were taken.

Participants aged 50 years and older have had radiographs taken of the thoracic and lumbar spine. Blood, urine and DNA samples have been collected from participants in some centers at baseline, year 5 and year 10 follow-up.